Nature Communications (May 2021)
Lying in wait: the resurgence of dengue virus after the Zika epidemic in Brazil
- Anderson Fernandes Brito,
- Lais Ceschini Machado,
- Rachel J. Oidtman,
- Márcio Junio Lima Siconelli,
- Quan Minh Tran,
- Joseph R. Fauver,
- Rodrigo Dias de Oliveira Carvalho,
- Filipe Zimmer Dezordi,
- Mylena Ribeiro Pereira,
- Luiza Antunes de Castro-Jorge,
- Elaine Cristina Manini Minto,
- Luzia Márcia Romanholi Passos,
- Chaney C. Kalinich,
- Mary E. Petrone,
- Emma Allen,
- Guido Camargo España,
- Angkana T. Huang,
- Derek A. T. Cummings,
- Guy Baele,
- Rafael Freitas Oliveira Franca,
- Benedito Antônio Lopes da Fonseca,
- T. Alex Perkins,
- Gabriel Luz Wallau,
- Nathan D. Grubaugh
Affiliations
- Anderson Fernandes Brito
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health, Yale University
- Lais Ceschini Machado
- Department of Entomology, Aggeu Magalhaẽs Institute, Fiocruz
- Rachel J. Oidtman
- Department of Biological Sciences and Eck Institute for Global Health, University of Notre Dame
- Márcio Junio Lima Siconelli
- Internal Medicine Department, Ribeirão Preto Medical School, University of São Paulo
- Quan Minh Tran
- Department of Biological Sciences and Eck Institute for Global Health, University of Notre Dame
- Joseph R. Fauver
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health, Yale University
- Rodrigo Dias de Oliveira Carvalho
- Department of Entomology, Aggeu Magalhaẽs Institute, Fiocruz
- Filipe Zimmer Dezordi
- Department of Entomology, Aggeu Magalhaẽs Institute, Fiocruz
- Mylena Ribeiro Pereira
- Department of Virology and Experimental Therapy, Aggeu Magalhaes Institute, Fiocruz
- Luiza Antunes de Castro-Jorge
- Internal Medicine Department, Ribeirão Preto Medical School, University of São Paulo
- Elaine Cristina Manini Minto
- Municipal Health Secretary from Ribeirão Preto
- Luzia Márcia Romanholi Passos
- Municipal Health Secretary from Ribeirão Preto
- Chaney C. Kalinich
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health, Yale University
- Mary E. Petrone
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health, Yale University
- Emma Allen
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health, Yale University
- Guido Camargo España
- Department of Biological Sciences and Eck Institute for Global Health, University of Notre Dame
- Angkana T. Huang
- Department of Biology and Emerging Pathogens Institute, University of Florida
- Derek A. T. Cummings
- Department of Biology and Emerging Pathogens Institute, University of Florida
- Guy Baele
- KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Evolutionary and Computational Virology
- Rafael Freitas Oliveira Franca
- Department of Virology and Experimental Therapy, Aggeu Magalhaes Institute, Fiocruz
- Benedito Antônio Lopes da Fonseca
- Internal Medicine Department, Ribeirão Preto Medical School, University of São Paulo
- T. Alex Perkins
- Department of Biological Sciences and Eck Institute for Global Health, University of Notre Dame
- Gabriel Luz Wallau
- Department of Entomology, Aggeu Magalhaẽs Institute, Fiocruz
- Nathan D. Grubaugh
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health, Yale University
- DOI
- https://doi.org/10.1038/s41467-021-22921-7
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 13
Abstract
Zika and dengue incidence in the Americas declined in 2017–2018, but dengue resurged in 2019 in Brazil. This study uses epidemiological, climatological and genomic data to show that the decline of dengue may be explained by protective immunity from pre-exposure to ZIKV and/or DENV in prior years.
