What’s the use?

eLife (Oct 2021)

Affiliations

Jason M Fletcher: ORCiD; Department of Sociology, University of Wisconsin-Madison, Madison, United States; La Follette School of Public Affairs, University of Wisconsin-Madison, Madison, United States; Center for Demography of Health and Aging, University of Wisconsin-Madison, Madison, United States
Yuchang Wu: ORCiD; Center for Demography of Health and Aging, University of Wisconsin-Madison, Madison, United States; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, United States
Qiongshi Lu: ORCiD; Center for Demography of Health and Aging, University of Wisconsin-Madison, Madison, United States; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, United States

Abstract

A theoretical framework predicts that using polygenic screening to select embryos against traits that depend on many genes has few benefits.