A Novel Probe for Spliceosomal Proteins that Induces Autophagy and Death of Melanoma Cells Reveals New Targets for Melanoma Drug Discovery

• Manikandan Palrasu,
• Anna M. Knapinska,
• Juan Diez,
• Lyndsay Smith,
• Travis LaVoi,
• Mac Giulianotti,
• Richard A. Houghten,
• Gregg B. Fields,
• Dmitriy Minond

Affiliations

Manikandan Palrasu

Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, AL, USA

Anna M. Knapinska

Department of Chemistry & Biochemistry, Center for Molecular Biology & Biotechnology, Florida Atlantic University, Jupiter, FL, USA

Juan Diez

Rumbaugh-Goodwin Institute for Cancer Research, Nova Southeastern University, Fort Lauderdale, FL, USA

Lyndsay Smith

Department of Chemistry & Biochemistry, Center for Molecular Biology & Biotechnology, Florida Atlantic University, Jupiter, FL, USA

Travis LaVoi

Torrey Pines Institute for Molecular Studies, Port St. Lucie, FL, USA

Mac Giulianotti

Torrey Pines Institute for Molecular Studies, Port St. Lucie, FL, USA

Richard A. Houghten

Torrey Pines Institute for Molecular Studies, Port St. Lucie, FL, USA

Gregg B. Fields

Department of Chemistry & Biochemistry, Center for Molecular Biology & Biotechnology, Florida Atlantic University, Jupiter, FL, USA

Dmitriy Minond

Rumbaugh-Goodwin Institute for Cancer Research, Nova Southeastern University, Fort Lauderdale, FL, USA; Dr. Kiran C. Patel College of Allopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, USA