The concurrent occurrence of neuroendocrine tumour and gastrointestinal stromal tumours

Abstract

Gastrointestinal neuroendocrine tumours are hypothesised to arise from cells in the gastrointestinal tract's diffuse neuroendocrine system. The occurrence of Gastrointestinal Stromal Tumours (GIST) along with other primary gastrointestinal malignancies is not common. More than 60% of the GIST occurs in stomach and 37% in jejunum. GIST can coexist with single well-differentiated, occasional neuroendocrine tumours of small size. In terms of preventing metastatic illness, an adequate first curative approach combined with meticulous follow-up appears to have a substantial effect. Although a synchronous incidence of gastrointestinal tumours without any associated disorders is uncommon, any gastrointestinal tumour should be thoroughly investigated to rule it out. We report the case of coexistence of a high risk of neuroendocrine tumour along with gastrointestinal tumour in a 30-year-old male patient. Postoperative chemotherapy with imatinib 40 mg once a day for 6 months was given and followed-up. Patient had no recurrence for 6 months.

Keywords

• neuroendocrine tumour
• gastrointestinal stromal tumour
• synchronous multicentric origin