Effect of complications on survival after lung cancer surgery

Abstract

Purpose: This study aims to investigate the effect of complications on survival after lung cancer surgery. Materials and Methods: This is a retrospective study of 802 patients who underwent surgical operations for lung cancer at two centers between January 2002 and December 2019. All patients were retrospectively evaluated according to age, gender, cancer stage, surgical technique, biochemical tests, pulmonary function tests, pulmonary risk index, length of the hospital stay, and the existing number of complications. Results: In total, 802 patients (%84 males, %16 females) with a mean age of 60 years (range 19-88 years) were included in the study. 5-year overall survival rate was 62.3%. 224 complications occurred in 180 patients (22.4%). The ten most common complications, respectively, were prolonged air leak (54), pneumonia (22), arrhythmia (19), respiratory failure (15), hemorrhage (17), atelectasis (10), pneumothorax-expansion defect (7), arrest (7) bronchopleural fistula (7), subileus-ileus (6). Cancer stage, the existing number of complications, advancing age, and tumor size are parameters that significantly affect survival. The occurs of one or more complications significantly adversely affects survival. Conclusion: Although the morbidity and mortality of lung cancer surgery have decreased in recent years, it is still high. Advanced stage lung cancer, advancing age, enlargement of tumor size and occurs of complications that negatively affect survival. Careful preoperative preparation may play a role in increasing long-term survival, as well as preventing complications, and decreasing early mortality.

Keywords

• lung cancer
• postoperative
• surgery
• complications
• akciğer kanseri
• ameliyat sonrası
• cerrahi
• komplikasyonlar