American Journal of Ophthalmology Case Reports (Jun 2025)

Presumed Ocular tuberculosis masquerading as autoimmune retinopathy

  • Si-meng Hou,
  • Qian Liu,
  • Xiao-hui Zhang,
  • Xiao-yan Peng,
  • Hui-yang Zeng

DOI
https://doi.org/10.1016/j.ajoc.2025.102296
Journal volume & issue
Vol. 38
p. 102296

Abstract

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Purpose: To report a case of tuberculosis (TB) infection with an unusual posterior segment manifestation that mimicked autoimmune retinopathy (AIR). Observation: A 36-year-old male presented with blurred vision and constriction of visual field (VF) in both eyes for over 2 weeks. Multimodal imaging suggested he had AIR-like retinopathy; however, the initial local/systemic steroid treatment worsened his condition. He later tested positive for TB infection and received one month of anti-tuberculosis (ATT) monotherapy, followed by combined steroid treatment for an additional 5 months. He was followed up 12 months after treatment, demonstrating significantly improved visual function and restoration of macular anatomy. Conclusions: This case underscores the need to consider intraocular TB as a potential mimic of AIR, highlighting the importance of ruling out active infections before diagnosing AIR.

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