Nature Communications (Mar 2023)
Telomere length associates with chronological age and mortality across racially diverse pulmonary fibrosis cohorts
- Ayodeji Adegunsoye,
- Chad A. Newton,
- Justin M. Oldham,
- Brett Ley,
- Cathryn T. Lee,
- Angela L. Linderholm,
- Jonathan H. Chung,
- Nicole Garcia,
- Da Zhang,
- Rekha Vij,
- Robert Guzy,
- Renea Jablonski,
- Remzi Bag,
- Rebecca S. Voogt,
- Shwu-Fan Ma,
- Anne I. Sperling,
- Ganesh Raghu,
- Fernando J. Martinez,
- Mary E. Strek,
- Paul J. Wolters,
- Christine Kim Garcia,
- Brandon L. Pierce,
- Imre Noth
Affiliations
- Ayodeji Adegunsoye
- Section of Pulmonary & Critical Care, Department of Medicine, The University of Chicago
- Chad A. Newton
- Division of Pulmonary & Critical Care Medicine, Department of Internal Medicine, University of Texas Southwestern
- Justin M. Oldham
- Division of Pulmonary, Critical Care & Sleep Medicine, Department of Medicine, University of California, Davis
- Brett Ley
- Section of Pulmonary & Critical Care Medicine, Department of Medicine, University of California
- Cathryn T. Lee
- Section of Pulmonary & Critical Care, Department of Medicine, The University of Chicago
- Angela L. Linderholm
- Division of Pulmonary, Critical Care & Sleep Medicine, Department of Medicine, University of California, Davis
- Jonathan H. Chung
- Department of Radiology, The University of Chicago
- Nicole Garcia
- Section of Pulmonary & Critical Care, Department of Medicine, The University of Chicago
- Da Zhang
- Division of Pulmonary, Allergy and Critical Care Medicine, Columbia University Medical Center
- Rekha Vij
- Section of Pulmonary & Critical Care, Department of Medicine, The University of Chicago
- Robert Guzy
- Section of Pulmonary & Critical Care, Department of Medicine, The University of Chicago
- Renea Jablonski
- Section of Pulmonary & Critical Care, Department of Medicine, The University of Chicago
- Remzi Bag
- Section of Pulmonary & Critical Care, Department of Medicine, The University of Chicago
- Rebecca S. Voogt
- Section of Pulmonary & Critical Care, Department of Medicine, The University of Chicago
- Shwu-Fan Ma
- Division of Pulmonary & Critical Care Medicine, Department of Medicine, University of Virginia
- Anne I. Sperling
- Section of Pulmonary & Critical Care, Department of Medicine, The University of Chicago
- Ganesh Raghu
- Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington Medical Center
- Fernando J. Martinez
- Pulmonary Critical Care Medicine, Weill Cornell Medicine
- Mary E. Strek
- Section of Pulmonary & Critical Care, Department of Medicine, The University of Chicago
- Paul J. Wolters
- Section of Pulmonary & Critical Care Medicine, Department of Medicine, University of California
- Christine Kim Garcia
- Division of Pulmonary, Allergy and Critical Care Medicine, Columbia University Medical Center
- Brandon L. Pierce
- Department of Public Health Sciences, The University of Chicago
- Imre Noth
- Division of Pulmonary & Critical Care Medicine, Department of Medicine, University of Virginia
- DOI
- https://doi.org/10.1038/s41467-023-37193-6
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 13
Abstract
The association of telomere length with age and mortality across racially diverse pulmonary fibrosis populations is unknown. Here, the authors show that leukocyte telomere length associates with chronologic age and is predictive of mortality in pulmonary fibrosis across racial groups.
