Nature Communications (Mar 2017)
Fluorene-9-bisphenol is anti-oestrogenic and may cause adverse pregnancy outcomes in mice
- Zhaobin Zhang,
- Ying Hu,
- Jilong Guo,
- Tong Yu,
- Libei Sun,
- Xuan Xiao,
- Desheng Zhu,
- Tsuyoshi Nakanishi,
- Youhei Hiromori,
- Junyu Li,
- Xiaolin Fan,
- Yi Wan,
- Siyu Cheng,
- Jun Li,
- Xuan Guo,
- Jianying Hu
Affiliations
- Zhaobin Zhang
- College of Urban and Environmental Sciences, MOE Laboratory for Earth Surface Process, Peking University
- Ying Hu
- College of Urban and Environmental Sciences, MOE Laboratory for Earth Surface Process, Peking University
- Jilong Guo
- College of Urban and Environmental Sciences, MOE Laboratory for Earth Surface Process, Peking University
- Tong Yu
- College of Urban and Environmental Sciences, MOE Laboratory for Earth Surface Process, Peking University
- Libei Sun
- College of Urban and Environmental Sciences, MOE Laboratory for Earth Surface Process, Peking University
- Xuan Xiao
- College of Urban and Environmental Sciences, MOE Laboratory for Earth Surface Process, Peking University
- Desheng Zhu
- Laboratory Animal Centre, Peking University
- Tsuyoshi Nakanishi
- Laboratory of Hygienic Chemistry and Molecular Toxicology, Gifu Pharmaceutical University
- Youhei Hiromori
- Laboratory of Hygienic Chemistry and Molecular Toxicology, Gifu Pharmaceutical University
- Junyu Li
- College of Urban and Environmental Sciences, MOE Laboratory for Earth Surface Process, Peking University
- Xiaolin Fan
- College of Urban and Environmental Sciences, MOE Laboratory for Earth Surface Process, Peking University
- Yi Wan
- College of Urban and Environmental Sciences, MOE Laboratory for Earth Surface Process, Peking University
- Siyu Cheng
- College of Urban and Environmental Sciences, MOE Laboratory for Earth Surface Process, Peking University
- Jun Li
- Laboratory Animal Centre, Peking University
- Xuan Guo
- College of Urban and Environmental Sciences, MOE Laboratory for Earth Surface Process, Peking University
- Jianying Hu
- College of Urban and Environmental Sciences, MOE Laboratory for Earth Surface Process, Peking University
- DOI
- https://doi.org/10.1038/ncomms14585
- Journal volume & issue
-
Vol. 8,
no. 1
pp. 1 – 13
Abstract
Bisphenol A is used in the production of many plastic products, but has adverse health effects and is therefore being replaced. Here the authors show that its substitute, fluorene-9-bisphenol, is released from commercial plastic bottles into drinking water, and has anti-oestrogenic effects in mice.
