Medical Mycology Case Reports (Dec 2020)

A case of rhinocerebral mucormycosis with brain abscess drained by endoscopic endonasal skull base surgery

  • Kensuke Uraguchi,
  • Kenichi Kozakura,
  • Satoshi Oka,
  • Takaya Higaki,
  • Seiichiro Makihara,
  • Toshi Imai,
  • Akira Doi,
  • Tsuyoshi Ohta,
  • Shin Kariya,
  • Kazunori Nishizaki

Journal volume & issue
Vol. 30
pp. 22 – 25

Abstract

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A 70-year-old Japanese man undergoing remission induction therapy for acute monocytic leukemia (AML-M5b) developed fever and headache, and was started on antibiotics and liposomal amphotericin B (L-AMB). There was no improvement, and computed tomography and contrast-enhanced magnetic resonance imaging revealed acute rhinosinusitis and brain abscess. Successful endoscopic endonasal surgery was performed at this point, providing drainage for the rhinosinusitis and abscess. Histopathological findings showed the mucormycosis.

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