EXPRESSION OF ESTROGEN AND PROGESTERONE RECEPTORS BY HUMAN ENDOMETRIAL MULTIPOTENT MESENCHYMAL STROMAL/STEM CELLS in vitro UNDER HYPOXIA CONDITIONS

Abstract

The aim of the study was to investigate the level of estrogen (ESR1, ESR2) and progesterone (PGR) receptors expression in the primary culture of endometrial multipotent mesenchymal stromal/stem cells endometrial multipotent mesenchymal stem cells and during in vitro cultivation under different athmospheric oxygen content. The dynamics of changes in the level of expression of the sex hormones receptors in the primary culture and during cultivation under different oxygen content in the athmosphere was shown.

Keywords

• human endometrium
• multipotent mesenchymal stromal cells
• expression of the receptors to the sex hormones
• estrogen
• progesterone.