A case of endometrial carcinoma and pregnancy in a cat

Abstract

This case report describes a rare condition of a pregnant cat that has endometrial carcinoma. A 5-year-old cat was presented because of vaginal discharge on the 40th day after the mating. USG examination revealed small embryonic structures, and thickened endometrium. It was decided to perform an ovariohysterectomy operation. The ovaries and uterus were sent to the laboratory for histopathological examination. The uterine mucosa showed papillary growth and atypical cells with mild to moderate anisokaryosis and occasional mitotic figures. The estrogen beta receptor was mildly positive in some neoplastic epithelium and stromal cells. The progesterone receptor was significantly positive in the lamellar layers of the placenta and myometrium but only slight positivity was observed in neoplastic cells. In summary, the gestational sacs were still at the implantation stage on the 40th day after mating may have been due to the carcinoma in the uterine endometrium and implantation could not occur for this reason. Our case might suggest that estrogen-dependent uterine tissue negatively affects embryonal development in cats and thus pregnancy couldn"t be completed properly.

Keywords

• endometrial carcinoma
• neoplasm
• queen
• pregnancy