The renal vascular resistive index as a predictor of acute kidney injury in children of the first year of life in congenital heart surgery with cardiopulmonary bypass

Abstract

The objective was to evaluate the renal vascular resistive index as a predictor of acute kidney injury in children of the first year of life in congenital heart surgery with cardiopulmonary bypass. Materials and methods. A single-center retrospective study included 150 patients with congenital heart disease (CHD), whose renal vascular resistive index (RVRI) was assessed at the stages of surgical interventions (before surgery, 6 hours after the end of cardiopulmonary bypass (CPB) and the 1st day after surgery). Acute kidney injury (AKI) was diagnosed according to the KDIGO criteria. To achieve comparability of the obtained groups, pseudo-randomization was performed. After compensating for the uneven distribution of cofounders, groups of patients comparable in number were obtained (n= 52 in both groups). Results. The renal vascular resistive index at the stages of surgical intervention did not differ among patients with and without acute kidney injury. The baseline of creatinine was higher in the group without AKI, however, starting from the 1st postoperative day, it prevailed in the group with AKI. The chances of developing AKI in male patients were 74% lower. Conclusion. The absence of a predictive ability of the renal vascular resistive index in acute kidney injury in children aged 1 month to 1 year with congenital heart disease operated with cardiopulmonary bypass was demonstrated.

Keywords

• congenital heart disease
• cardiopulmonary bypass
• resistive index
• acute kidney injury