Nature Communications (Jul 2021)

Parallel processing of working memory and temporal information by distinct types of cortical projection neurons

  • Jung Won Bae,
  • Huijeong Jeong,
  • Young Ju Yoon,
  • Chan Mee Bae,
  • Hyeonsu Lee,
  • Se-Bum Paik,
  • Min Whan Jung

DOI
https://doi.org/10.1038/s41467-021-24565-z
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 18

Abstract

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Intratelencephalic and pyramidal tract neurons are two major types of cortical excitatory neurons that project to cortical and subcortical structures. The authors show that in the prefrontal cortex the two populations have different roles for the maintenance of working memory and for tracking the passage of time.