A heavy metal P-type ATPase OsHMA4 prevents copper accumulation in rice grain

Xin-Yuan Huang; Fenglin Deng; Naoki Yamaji; Shannon R.M. Pinson; Miho Fujii-Kashino; John Danku; Alex Douglas; Mary Lou Guerinot; David E. Salt; Jian Feng Ma

doi:10.1038/ncomms12138

Nature Communications (Jul 2016)

A heavy metal P-type ATPase OsHMA4 prevents copper accumulation in rice grain

Xin-Yuan Huang,
Fenglin Deng,
Naoki Yamaji,
Shannon R.M. Pinson,
Miho Fujii-Kashino,
John Danku,
Alex Douglas,
Mary Lou Guerinot,
David E. Salt,
Jian Feng Ma

Affiliations

Xin-Yuan Huang: Institute of Biological and Environmental Sciences, University of Aberdeen
Fenglin Deng: Institute of Plant Science and Resources, Okayama University
Naoki Yamaji: Institute of Plant Science and Resources, Okayama University
Shannon R.M. Pinson: USDA–ARS Dale Bumpers National Rice Research Center
Miho Fujii-Kashino: Institute of Plant Science and Resources, Okayama University
John Danku: Institute of Biological and Environmental Sciences, University of Aberdeen
Alex Douglas: Institute of Biological and Environmental Sciences, University of Aberdeen
Mary Lou Guerinot: Department of Biological Sciences, Dartmouth College
David E. Salt: Institute of Biological and Environmental Sciences, University of Aberdeen
Jian Feng Ma: Institute of Plant Science and Resources, Okayama University

DOI: https://doi.org/10.1038/ncomms12138
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 13

Abstract

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Copper (Cu) is an essential mineral nutrient but high concentrations in rice grain can cause toxicity. Here the authors provide evidence that natural variation in rice grain Cu concentration is caused by altered sequestration of Cu into root vacuoles due to a single amino acid substitution in the OsHMA4 transporter.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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