Arquivos de Neuro-Psiquiatria (Oct 2012)

Epilepsy with onset at over 50 years of age: clinical and electroencephalographic characteristics

  • Glória Maria Almeida Souza Tedrus,
  • Lineu Corrêa Fonseca,
  • Elizardo Nogueira Junior,
  • Daniele Pazetto

DOI
https://doi.org/10.1590/S0004-282X2012001000006
Journal volume & issue
Vol. 70, no. 10
pp. 780 – 785

Abstract

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Epilepsy in older individuals has an elevated incidence. The objective of the present work was to evaluate the clinical, EEG and brain imaging aspects in patients showing late-onset epilepsy. Fifty-five patients with late-onset epilepsy (older than 50 years) were evaluated. They were composed of two groups according to the onset age of the epilepsy seizure (ES): 51-60 (G51-60) and over 60 (G60+) years. Focal ES predominated although they were less frequent in G60+. The occurrence of status epilepticus was high and more frequent in G60+ whereas seizures in series predominated in G51-60. Symptomatic epilepsy was more frequent and the vascular etiology predominated. Epileptiform activity was associated with a greater number of ES, and background activity abnormalities were more frequent in G60+. In conclusion, epilepsy with onset at over 50 was predominantly focal and symptomatic, with a high occurrence of status epilepticus and of seizures in series.

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