Clinical and Experimental Obstetrics & Gynecology (Sep 2022)

COVID-19 Vaccination and Pregnancy

  • Natalia Ignaszak-Kaus,
  • Karolina Chmaj-Wierzchowska,
  • Katarzyna Wszołek,
  • Maciej Wilczak

DOI
https://doi.org/10.31083/j.ceog4910220
Journal volume & issue
Vol. 49, no. 10
p. 220

Abstract

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Objectives: A review to assess the safety, efficacy, COVID-19 vaccination acceptance and awareness in pregnant women. Machanism: Pregnant women diagnosed with COVID-19 are characterized by more frequent hospitalization in intensive care units and are at three times higher risk of preterm; their newborns more often need invasive ventilation. Vaccination is the most effective preventive measures against SARS-CoV-2, but there are still questions about safety and immune response. Pregnant women were not included in study groups during phase III clinical trials. Findings in Brief: Vaccination during pregnancy is not associated with an increased risk of obstetric or neonatal complications; scientific communities recommend vaccination for pregnant women, those planning for pregnancy and those who are breastfeeding. Unfortunately, knowledge regarding COVID-19 vaccination and willingness to take vaccine during pregnancy is low. Conclusions: General practitioners and obstetricians have a large role in increasing public awareness of COVID-19 vaccination. No evidence of teratogenicity of the vaccine has been found.

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