Journal of Pain Research (Feb 2021)

Current Perspectives on Neurostimulation for the Management of Chronic Low Back Pain: A Narrative Review

  • Provenzano DA,
  • Heller JA,
  • Hanes MC

Journal volume & issue
Vol. Volume 14
pp. 463 – 479

Abstract

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David A Provenzano,1,2 Jared A Heller,3 Michael C Hanes4 1Pain Diagnostics and Interventional Care, Sewickley, PA, USA; 2Western PA Surgery Center, Wexford, PA, USA; 3Washington & Jefferson College, Washington, PA, USA; 4Jax Spine & Pain Centers, Jacksonville, FL, USACorrespondence: David A ProvenzanoPain Diagnostics and Interventional Care, 301 Ohio River Blvd Suite 203, Sewickley, PA, 15143, USATel +1 412-221-7640Fax +1 412-490-7640Email [email protected]: Neurostimulation techniques for the treatment of chronic low back pain (LBP) have been rapidly evolving; however, questions remain as to which modalities provide the most efficacious and durable treatment for intractable axial symptoms. Modalities of spinal cord stimulation, such as traditional low-frequency paresthesia based, high-density or high dose (HD), burst, 10-kHz high-frequency therapy, closed-loop, and differential target multiplexed, have been limitedly studied to determine their efficacy for the treatment of axial LBP. In addition, stimulation methods that target regions other than the spinal cord, such as medial branch nerve stimulation of the multifidus muscles and the dorsal root ganglion may also be viable treatment options. Here, current scientific evidence behind neurostimulation techniques have been reviewed with a focus on the management of chronic axial LBP.Keywords: spinal cord stimulation, chronic, axial, neuromodulation

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