Rapid Construction of Liquid-like Surfaces via Single-Cycle Polymer Brush Grafting for Enhanced Antifouling in Microfluidic Systems
Feng Wu,
Jing Xu,
Yuanyuan Liu,
Hua Sun,
Lishang Zhang,
Yixuan Liu,
Weiwei Wang,
Fali Chong,
Dan Zou,
Shuli Wang
Affiliations
Feng Wu
School of Physics and New Energy, Xuzhou University of Technology, Xuzhou 221018, China
Jing Xu
Medical Laboratory Department, The First People’s Hospital of Xuzhou, Xuzhou 221116, China
Yuanyuan Liu
School of Material and Chemical Engineering, Xuzhou University of Technology, Xuzhou 221018, China
Hua Sun
School of Material and Chemical Engineering, Xuzhou University of Technology, Xuzhou 221018, China
Lishang Zhang
School of Physics and New Energy, Xuzhou University of Technology, Xuzhou 221018, China
Yixuan Liu
School of Physics and New Energy, Xuzhou University of Technology, Xuzhou 221018, China
Weiwei Wang
School of Physics and New Energy, Xuzhou University of Technology, Xuzhou 221018, China
Fali Chong
School of Physics and New Energy, Xuzhou University of Technology, Xuzhou 221018, China
Dan Zou
School of Health Management, Xihua University, Chengdu 610039, China
Shuli Wang
Fujian Engineering Research Center for Solid-State Lighting, Department of Electronic Science, School of Electronic Science and Engineering, Xiamen University, Xiamen 361005, China
Liquid-like surfaces have demonstrated immense potential in their ability to resist cell adhesion, a critical requirement for numerous applications across various domains. However, the conventional methodologies for preparing liquid-like surfaces often entail a complex multi-step polymer brush modification process, which is not only time-consuming but also presents significant challenges. In this work, we developed a single-cycle polymer brush modification strategy to build liquid-like surfaces by leveraging high-molecular-weight bis(3-aminopropyl)-terminated polydimethylsiloxane, which significantly simplifies the preparation process. The resultant liquid-like surface is endowed with exceptional slipperiness, effectively inhibiting bacterial colonization and diminishing the adherence of platelets. Moreover, it offers promising implications for reducing the dependency on anticoagulants in microfluidic systems constructed from PDMS, all while sustaining its antithrombotic attributes.
