G3: Genes, Genomes, Genetics (Mar 2023)

Cryptic genetic variation of expression quantitative trait locus architecture revealed by genetic perturbation in <i>Caenorhabditis elegans</i>

  • Marijke H van Wijk,
  • Joost A G Riksen,
  • Mark Elvin,
  • Gino B Poulin,
  • Muhammad I Maulana,
  • Jan E Kammenga,
  • Basten L Snoek,
  • Mark G Sterken

DOI
https://doi.org/10.1093/g3journal/jkad050
Journal volume & issue
Vol. 13, no. 5

Abstract

Read online

AbstractGenetic perturbation in different genetic backgrounds can cause a range of phenotypes within a species. These phenotypic differences can be the result of the interaction between the genetic background and the perturbation. Previously, we reported that perturbation of gld-1Caenorhabditis eleganscis-trans-gld-1gld-1gld-1