Recent Applications of Polymer Supported Organometallic Catalysts in Organic Synthesis

Abstract

Recent developments concerning the application of polymer supported organometallic reagents in solid phase synthesis are reviewed, with a special focus on methodology for carbon-carbon formation. Examples of reactions that are covered include the classical Suzuki, Sonogashira and Heck coupings, but also aryl amination, epoxide opening, rearrangements, metathesis and cyclopropanation. Applications in the field of asymmetric synthesis are also discussed.

Keywords

• polymer supported
• organometallic
• solid phase synthesis
• cross-coupling
• metathesis
• allylic substitution
• transfer hydrogenation
• aryl amination