Management of central nervous system relapse in a young patient affected by primary mediastinal large B‐cell lymphoma: A case report

Miriam Marangon; Beatrice Casadei; Alessandro Broccoli; Lisa Argnani; Michele Cavo; Pier Luigi Zinzani

doi:10.1002/ccr3.2706

Clinical Case Reports (Jun 2020)

Management of central nervous system relapse in a young patient affected by primary mediastinal large B‐cell lymphoma: A case report

Miriam Marangon,
Beatrice Casadei,
Alessandro Broccoli,
Lisa Argnani,
Michele Cavo,
Pier Luigi Zinzani

Affiliations

Miriam Marangon: Institute of Hematology “L. e A. Seràgnoli” University of Bologna Bologna Italy
Beatrice Casadei: Institute of Hematology “L. e A. Seràgnoli” University of Bologna Bologna Italy
Alessandro Broccoli: Institute of Hematology “L. e A. Seràgnoli” University of Bologna Bologna Italy
Lisa Argnani: Institute of Hematology “L. e A. Seràgnoli” University of Bologna Bologna Italy
Michele Cavo: Institute of Hematology “L. e A. Seràgnoli” University of Bologna Bologna Italy
Pier Luigi Zinzani: Institute of Hematology “L. e A. Seràgnoli” University of Bologna Bologna Italy

DOI: https://doi.org/10.1002/ccr3.2706
Journal volume & issue: Vol. 8, no. 6
pp. 933 – 937

Abstract

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Abstract In primary mediastinal large B‐cell lymphoma, central nervous system (CNS) relapse is an uncommon event with a dismal prognosis. We report about the successful management of CNS relapse with chemoimmunotherapy according to MATRix (methotrexate, cytarabine, thiotepa, and rituximab) protocol followed by autologous stem cell transplant.

Published in Clinical Case Reports

ISSN: 2050-0904 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Medicine (General)
Website: https://onlinelibrary.wiley.com/journal/20500904

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Abstract

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