Comparison of Central Corneal Thickness and Retinal Nerve Fiber Layer Thickness and Ganglion Cell Complex in Patients with Ocular Hypertension

Abstract

Purpose: To evaluate the correlation of retinal nerve fiber layer thickness (RNFLT) with ganglion cell complex and central corneal thickness (CCT) measurements in patients with ocular hypertension and healthy subjects. Material and Method: Seventy-six eyes of 38 patients with ocular hypertension and 76 eyes of 38 healthy subjects were included in this study. Both groups were stratified by CCT into 579 µm (p0.05). In the control group, there was no significant correlation between CCT and RNFLT (average, superior average, inferior average) measurements (p>0.05). There was no significant correlation between CCT and average, superior average, inferior average ganglion cell complex in both groups. Discussion: Ocular hypertension patients with CCT <550 µm may represent patients who have very early undetected glaucoma. This may in part explain the higher risk of these patients for progression to glaucoma. (Turk J Ophthalmol 2013; 43: 385-90)

Keywords

• Ocular hypertension
• retinal nerve fiber layer
• central corneal thickness
• ganglion cell complex