A Calcium Enterolith in a Patient with Crohn’s Disease and Its In Vitro Dissolubility in Citric Acid

Masaya Iwamuro; Haruo Urata; Sakiko Hiraoka; Masayasu Ohmori; Yoshitaka Kondo; Yoshiro Kawahara; Hiroyuki Okada

doi:10.1155/2017/2951547

Case Reports in Gastrointestinal Medicine (Jan 2017)

A Calcium Enterolith in a Patient with Crohn’s Disease and Its In Vitro Dissolubility in Citric Acid

Masaya Iwamuro,
Haruo Urata,
Sakiko Hiraoka,
Masayasu Ohmori,
Yoshitaka Kondo,
Yoshiro Kawahara,
Hiroyuki Okada

Affiliations

Masaya Iwamuro: Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan
Haruo Urata: Central Research Laboratory, Okayama University Medical School, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan
Sakiko Hiraoka: Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan
Masayasu Ohmori: Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan
Yoshitaka Kondo: Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan
Yoshiro Kawahara: Department of Endoscopy, Okayama University Hospital, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan
Hiroyuki Okada: Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan

DOI: https://doi.org/10.1155/2017/2951547
Journal volume & issue: Vol. 2017

Abstract

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The microstructure and dissolubility of a calcified enterolith and enterolith pieces removed from a 26-year-old Japanese woman with Crohn’s disease were analyzed using scanning electron microscopy and energy dispersive X-ray spectroscopy. The enterolith showed a multilayered structure with fatty acid calcium and magnesium phosphate. The amount of calcium, magnesium, and phosphate decreased after they were immersed in a citric acid solution, suggesting a potential contribution of acidic aqueous solution to elute inorganic substances contained in calcified enteroliths. This is the first study to investigate the in vitro dissolubility of calcified enteroliths induced by citric acid solution.

Published in Case Reports in Gastrointestinal Medicine

ISSN: 2090-6528 (Print); 2090-6536 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the digestive system. Gastroenterology
Website: https://onlinelibrary.wiley.com/journal/3142

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