TH Open (Jul 2023)
Levels of Fibrinogen Variants Are Altered in Severe COVID-19
- de Vries de Vries,
- Visser Visser,
- van Ommen van Ommen,
- Rokx Rokx,
- van Nood van Nood,
- van Gorp van Gorp,
- Goeijenbier Goeijenbier,
- van den Akker van den Akker,
- Endeman Endeman,
- Rijken Rijken,
- Kruip Kruip,
- Weggeman Weggeman,
- Koopman Koopman,
- de Maat de Maat
Affiliations
- de Vries de Vries
- ORCiD
- Department of Hematology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
- Visser Visser
- ORCiD
- Department of Hematology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
- van Ommen van Ommen
- Fibriant BV, Leiden, The Netherlands
- Rokx Rokx
- Department of Medical Microbiology and Infectious Diseases, Erasmus MC, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
- van Nood van Nood
- Department of Medical Microbiology and Infectious Diseases, Erasmus MC, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
- van Gorp van Gorp
- Department of Internal Medicine, Erasmus MC, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
- Goeijenbier Goeijenbier
- Department of Viroscience, Erasmus MC, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
- van den Akker van den Akker
- Department of Adult Intensive Care, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
- Endeman Endeman
- Department of Adult Intensive Care, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
- Rijken Rijken
- ORCiD
- Department of Hematology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
- Kruip Kruip
- Department of Hematology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
- Weggeman Weggeman
- Fibriant BV, Leiden, The Netherlands
- Koopman Koopman
- Fibriant BV, Leiden, The Netherlands
- de Maat de Maat
- ORCiD
- Department of Hematology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
- DOI
- https://doi.org/10.1055/a-2102-4521
- Journal volume & issue
-
Vol. 07,
no. 03
pp. e217 – e225
Abstract
Background Fibrinogen variants as a result of alternative messenger RNA splicing or protein degradation can affect fibrin(ogen) functions. The levels of these variants might be altered during coronavirus disease 2019 (COVID-19), potentially affecting disease severity or the thrombosis risk.
Keywords
