A segmentation model to detect cevical lesions based on machine learning of colposcopic images
Zhen Li,
Chu-Mei Zeng,
Yan-Gang Dong,
Ying Cao,
Li-Yao Yu,
Hui-Ying Liu,
Xun Tian,
Rui Tian,
Chao-Yue Zhong,
Ting-Ting Zhao,
Jia-Shuo Liu,
Ye Chen,
Li-Fang Li,
Zhe-Ying Huang,
Yu-Yan Wang,
Zheng Hu,
Jingjing Zhang,
Jiu-Xing Liang,
Ping Zhou,
Yi-Qin Lu
Affiliations
Zhen Li
Department of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, China
Chu-Mei Zeng
Department of Obstetrics and gynecology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510062, China
Yan-Gang Dong
Institute for Brain Research and Rehabilitation, the South China Normal University, Guangzhou, Guangdong, 510631, China
Ying Cao
Department of Obstetrics and Gynecology, Academician expert workstation, The Central Hospital of Wuhan, Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei, 430014, China
Li-Yao Yu
Department of Obstetrics and Gynecology, Academician expert workstation, The Central Hospital of Wuhan, Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei, 430014, China
Hui-Ying Liu
Department of Obstetrics and gynecology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510062, China
Xun Tian
Department of Obstetrics and Gynecology, Academician expert workstation, The Central Hospital of Wuhan, Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei, 430014, China
Rui Tian
the Generulor Company Bio-X Lab, Zhuhai, Guangdong, 519060, China
Chao-Yue Zhong
the Generulor Company Bio-X Lab, Zhuhai, Guangdong, 519060, China
Ting-Ting Zhao
the Generulor Company Bio-X Lab, Zhuhai, Guangdong, 519060, China
Jia-Shuo Liu
Department of Obstetrics and gynecology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510062, China
Ye Chen
Department of Obstetrics and gynecology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510062, China
Li-Fang Li
Department of Obstetrics and gynecology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510062, China
Zhe-Ying Huang
Department of Obstetrics and gynecology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510062, China
Yu-Yan Wang
Department of Obstetrics and gynecology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510062, China
Zheng Hu
Department of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, China
Jingjing Zhang
Department of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, China; Corresponding author.
Jiu-Xing Liang
Institute for Brain Research and Rehabilitation, the South China Normal University, Guangzhou, Guangdong, 510631, China; Corresponding authors.
Ping Zhou
Department of Gynecology, Dongguan Maternal and Child Hospital, Dongguan, Guangdong, 523057, China; Corresponding author.
Yi-Qin Lu
Department of Gynecology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 101121, China; Corresponding authors.
Background: Semantic segmentation is crucial in medical image diagnosis. Traditional deep convolutional neural networks excel in image classification and object detection but fall short in segmentation tasks. Enhancing the accuracy and efficiency of detecting high-level cervical lesions and invasive cancer poses a primary challenge in segmentation model development. Methods: Between 2018 and 2022, we retrospectively studied a total of 777 patients, comprising 339 patients with high-level cervical lesions and 313 patients with microinvasive or invasive cervical cancer. Overall, 1554 colposcopic images were put into the DeepLabv3+ model for learning. Accuracy, Precision, Specificity, and mIoU were employed to evaluate the performance of the model in the prediction of cervical high-level lesions and cancer. Results: Experiments showed that our segmentation model had better diagnosis efficiency than colposcopic experts and other artificial intelligence models, and reached Accuracy of 93.29 %, Precision of 87.2 %, Specificity of 90.1 %, and mIoU of 80.27 %, respectively. Conclution: The DeepLabv3+ model had good performance in the segmentation of cervical lesions in colposcopic post-acetic-acid images and can better assist colposcopists in improving the diagnosis.