Frontiers in Plant Science (Nov 2014)

Integrated Network Analysis and Effective Tools in Plant Systems Biology

  • Atsushi eFukushima,
  • Atsushi eFukushima,
  • Shigehiko eKanaya,
  • Kozo eNishida,
  • Kozo eNishida

DOI
https://doi.org/10.3389/fpls.2014.00598
Journal volume & issue
Vol. 5

Abstract

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One of the ultimate goals in plant systems biology is to elucidate the genotype-phenotype relationship in plant cellular systems. Integrated network analysis that combines omics data with mathematical models has received particular attention. Here we focus on the latest cutting-edge computational advances that facilitate their combination. We highlight (1) network visualization tools, (2) pathway analyses, (3) genome-scale metabolic reconstruction, and (4) the integration of high-throughput experimental data and mathematical models. Multi-omics data that contain the genome, transcriptome, proteome, and metabolome and mathematical models are expected to integrate and expand our knowledge of complex plant metabolisms.

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