Beneficial Diets and Pancreatic Cancer: Molecular Mechanisms and Clinical Practice

Yang Zhang; Tao Zhang; Wenbo Yang; Hongze Chen; Xinglong Geng; Guanqun Li; Hua Chen; Yongwei Wang; Le Li; Le Li; Bei Sun; Bei Sun

doi:10.3389/fonc.2021.630972

Frontiers in Oncology (May 2021)

Beneficial Diets and Pancreatic Cancer: Molecular Mechanisms and Clinical Practice

Yang Zhang,
Tao Zhang,
Wenbo Yang,
Hongze Chen,
Xinglong Geng,
Guanqun Li,
Hua Chen,
Yongwei Wang,
Le Li,
Le Li,
Bei Sun,
Bei Sun

Affiliations

Yang Zhang: Department of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China
Tao Zhang: Department of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China
Wenbo Yang: Department of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China
Hongze Chen: Department of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China
Xinglong Geng: Department of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China
Guanqun Li: Department of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China
Hua Chen: Department of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China
Yongwei Wang: Department of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China
Le Li: Department of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China
Le Li: Key Laboratory of Hepatosplenic Surgery, Ministry of Education, Harbin, China
Bei Sun: Department of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China
Bei Sun: Key Laboratory of Hepatosplenic Surgery, Ministry of Education, Harbin, China

DOI: https://doi.org/10.3389/fonc.2021.630972
Journal volume & issue: Vol. 11

Abstract

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Pancreatic cancer (PC) is a malignant tumor with high invasiveness, easy metastatic ability, and chemoresistance. Patients with PC have an extremely low survival rate due to the difficulty in early diagnosis. It is estimated that nearly 90% of PC cases are caused by environmental risk factors. Approximately 50% of PC cases are induced by an unhealthy diet, which can be avoided. Given this large attribution to diet, numerous studies have assessed the relationship between various dietary factors and PC. This article reviews three beneficial diets: a ketogenic diet (KD), a Mediterranean diet (MD), and a low-sugar diet. Their composition and impact mechanism are summarized and discussed. The associations between these three diets and PC were analyzed, and we aimed to provide more help and new insights for the prevention and treatment of PC.

Published in Frontiers in Oncology

ISSN: 2234-943X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.frontiersin.org/journals/oncology/

About the journal

Abstract

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