Prostaglandin F2A Disturbs Oogenesis by Causing Meiotic Spindle Damage

Abstract

According to recent data, prostaglandin F2 alpha can have a negative influence on meiosis during oogenesis. Previously, we have found that this prostaglandin may accelerate in a dosage-dependent way the postovulatory aging in ovulated mature oocytes, compromising the integrity of their meiotic spindles.

Keywords

• prostaglandin f2 alpha
• meiosis
• oogenesis
• oocytes
• female infertility
• meiotic spindle