1203 Blockade of the mechanistic target of rapamycin elicits rapid and lasting improvement of disease activity through restraining pro-inflammatory T cell lineage specification in patients with active SLE

• ANDRAS PERL,
• Hajra Tily,
• Zhi-wei Lai,
• Julie Yu,
• Stephen V Faraone,
• Ryan Kelly,
• Thomas Winans,
• Ivan Marchena,
• Ashwini Shadakshari,
• Maha Dawood,
• Ricardo Garcia,
• Lisa Francis,
• Paul E Phillips

Affiliations

ANDRAS PERL

Section of Rheumatology, Department of Medicine, State University of New York Upstate Medical University, Syracuse, New York, USA

Hajra Tily

Section of Rheumatology, Department of Medicine, State University of New York Upstate Medical University, Syracuse, New York, USA

Zhi-wei Lai

1Departments of Medicine, Microbiology, and Immunology, Biochemistry and Molecular Biology, Neuroscience and Physiology, and Pathology, SUNY Upstate Medical University, Syracuse, New York, USA

Julie Yu

27Amicus Therapeutics Inc., Cranbury, New Jersey, USA

Stephen V Faraone

Departments of Psychiatry and of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, New York, USA

Ryan Kelly

Division of Rheumatology, Departments of Medicine, Microbiology and Immunology, and Biochemistry and Molecular Biology, State University of New York, Upstate Medical University, College of Medicine, Syracuse, New York

Thomas Winans

Division of Rheumatology, Departments of Medicine, Microbiology and Immunology, and Biochemistry and Molecular Biology, State University of New York, Upstate Medical University, College of Medicine, Syracuse, New York

Ivan Marchena

Division of Rheumatology, Departments of Medicine, Microbiology and Immunology, and Biochemistry and Molecular Biology, State University of New York, Upstate Medical University, College of Medicine, Syracuse, New York

Ashwini Shadakshari

Division of Rheumatology, Departments of Medicine, Microbiology and Immunology, and Biochemistry and Molecular Biology, State University of New York, Upstate Medical University, College of Medicine, Syracuse, New York

Maha Dawood

Division of Rheumatology, Departments of Medicine, Microbiology and Immunology, and Biochemistry and Molecular Biology, State University of New York, Upstate Medical University, College of Medicine, Syracuse, New York

Ricardo Garcia

Division of Rheumatology, Departments of Medicine, Microbiology and Immunology, and Biochemistry and Molecular Biology, State University of New York, Upstate Medical University, College of Medicine, Syracuse, New York

Lisa Francis

Division of Rheumatology, Departments of Medicine, Microbiology and Immunology, and Biochemistry and Molecular Biology, State University of New York, Upstate Medical University, College of Medicine, Syracuse, New York

Paul E Phillips

Division of Rheumatology, Departments of Medicine, Microbiology and Immunology, and Biochemistry and Molecular Biology, State University of New York, Upstate Medical University, College of Medicine, Syracuse, New York