Improving Reporting of Clinical Studies Using the POSEIDON Criteria: POSORT Guidelines

Sandro C. Esteves; Sandro C. Esteves; Sandro C. Esteves; Alessandro Conforti; Sesh K. Sunkara; Luigi Carbone; Silvia Picarelli; Alberto Vaiarelli; Danilo Cimadomo; Laura Rienzi; Filippo Maria Ubaldi; Fulvio Zullo; Claus Yding Andersen; Raoul Orvieto; Peter Humaidan; Peter Humaidan; Carlo Alviggi

doi:10.3389/fendo.2021.587051

Frontiers in Endocrinology (Mar 2021)

Improving Reporting of Clinical Studies Using the POSEIDON Criteria: POSORT Guidelines

Sandro C. Esteves,
Sandro C. Esteves,
Sandro C. Esteves,
Alessandro Conforti,
Sesh K. Sunkara,
Luigi Carbone,
Silvia Picarelli,
Alberto Vaiarelli,
Danilo Cimadomo,
Laura Rienzi,
Filippo Maria Ubaldi,
Fulvio Zullo,
Claus Yding Andersen,
Raoul Orvieto,
Peter Humaidan,
Peter Humaidan,
Carlo Alviggi

Affiliations

Sandro C. Esteves: ANDROFERT, Andrology and Human Reproduction Clinic, Campinas, Brazil
Sandro C. Esteves: Department of Surgery (Division of Urology), University of Campinas (UNICAMP), Campinas, Brazil
Sandro C. Esteves: Faculty of Health, Aarhus University, Aarhus, Denmark
Alessandro Conforti: Department of Neuroscience, Reproductive Science and Odontostomatology, University of Naples, Federico II, Naples, Italy
Sesh K. Sunkara: Department of Women’s Health, Faculty of Life Sciences, King’s College London, London, United Kingdom
Luigi Carbone: Department of Neuroscience, Reproductive Science and Odontostomatology, University of Naples, Federico II, Naples, Italy
Silvia Picarelli: Department of Neuroscience, Reproductive Science and Odontostomatology, University of Naples, Federico II, Naples, Italy
Alberto Vaiarelli: Center for Reproductive Medicine, GENERA, Rome, Italy
Danilo Cimadomo: Center for Reproductive Medicine, GENERA, Rome, Italy
Laura Rienzi: Center for Reproductive Medicine, GENERA, Rome, Italy
Filippo Maria Ubaldi: Center for Reproductive Medicine, GENERA, Rome, Italy
Fulvio Zullo: Department of Neuroscience, Reproductive Science and Odontostomatology, University of Naples, Federico II, Naples, Italy
Claus Yding Andersen: Laboratory of Reproductive Biology, Faculty of Health and Medical Sciences, University Hospital of Copenhagen, Copenhagen, Denmark
Raoul Orvieto: Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Ramat Gan, Israel
Peter Humaidan: Faculty of Health, Aarhus University, Aarhus, Denmark
Peter Humaidan: Fertility Clinic Skive, Skive Regional Hospital, Skive, Denmark
Carlo Alviggi: Department of Neuroscience, Reproductive Science and Odontostomatology, University of Naples, Federico II, Naples, Italy

DOI: https://doi.org/10.3389/fendo.2021.587051
Journal volume & issue: Vol. 12

Abstract

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The POSEIDON (Patient-Oriented Strategies Encompassing IndividualizeD Oocyte Number) criteria were developed to help clinicians identify and classify low-prognosis patients undergoing assisted reproductive technology (ART) and provide guidance for possible therapeutic strategies to overcome infertility. Since its introduction, the number of published studies using the POSEIDON criteria has increased steadily. However, a critical analysis of existing evidence indicates inconsistent and incomplete reporting of critical outcomes. Therefore, we developed guidelines to help researchers improve the quality of reporting in studies applying the POSEIDON criteria. We also discuss the advantages of using the POSEIDON criteria in ART clinical studies and elaborate on possible study designs and critical endpoints. Our ultimate goal is to advance the knowledge concerning the clinical use of the POSEIDON criteria to patients, clinicians, and the infertility community.

Published in Frontiers in Endocrinology

ISSN: 1664-2392 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology
Website: https://www.frontiersin.org/journals/endocrinology

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