Journal of Pharmacy and Bioallied Sciences (Jan 2021)

To compare and analyze the potency of two topical anesthetic gels in reducing inferior alveolar injection pain in children of 8–12 years: A double-blinded clinical trial

  • Dharati Patel,
  • Banibrata Lahiri,
  • Mohamed Abd-Ellatif El-Patal,
  • Abdulfatah Alazmah,
  • Parth Patel,
  • Yousef H Abokhlifa

DOI
https://doi.org/10.4103/jpbs.JPBS_772_20
Journal volume & issue
Vol. 13, no. 5
pp. 646 – 650

Abstract

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Aim: To compare and analyze the clinical adequacy of two topical anesthetic gels, Precaine (8% lidocaine + 0.8% dibucaine) and Precaine B (20% benzocaine) in children before intraoral local anesthetic injections. Materials and Methods: This clinical study included thirty children who needed an inferior alveolar nerve block. They were divided into three groups: Group A: Precaine topical gel group, Group B: Precaine B topical gel Group, Group C: no anesthetic topical gel group (control group). These two effective topical gels were applied before giving intraoral local anesthesia, and afterward, the child's pain response was surveyed utilizing the Wong-Baker Faces Pain Rating Scale. The scores obtained were subjected to statistical analysis. Results: Intergroup comparison showed a significant mean difference between the control group and Precaine group (P > 0.05) as well as Precaine B group (P > 0.05). However, there is no significant difference obtained between Group A and Group B (P < 0.05). Conclusion: It is psychologically and clinically beneficial to apply a topical anesthetic agent before injecting any intraoral anesthesia. In this study, both anesthetic gels showed a nonsignificant difference in reducing inferior alveolar injection pain, but Precaine B shows more promising results than Precaine.

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