Nature Communications (Aug 2016)

Principal cell activity induces spine relocation of adult-born interneurons in the olfactory bulb

  • Vincent Breton-Provencher,
  • Karen Bakhshetyan,
  • Delphine Hardy,
  • Rodrigo Roberto Bammann,
  • Francesco Cavarretta,
  • Marina Snapyan,
  • Daniel Côté,
  • Michele Migliore,
  • Armen Saghatelyan

DOI
https://doi.org/10.1038/ncomms12659
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 16

Abstract

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The mechanism by which adult-born neurons quickly adjust olfactory bulb network functioning is not understood. Here the authors describe a novel form of structural plasticity in which mature spines relocate toward active mitral cell dendrite along spine head filopodia via AMPA and BDNF mediated signalling.