tHE FATTY ACID SPECTRUM OF TUMOR TISSUE IN CERVICAL CANCER WITH DIFFERENT HISTOPATHOLOGIC GRADES

Abstract

The higher fatty acid spectrum of tumor tissue in cervical cancer with different histopathologic grades was studied using the method of gas-liquid chromatography. Irrespective of differentiation grade, the high level of saturated fatty acids as compared to the control was observed mainly due to the increase in the amount of С14:0 and occurrence of С19:0. The increased level of monounsaturated fatty acids was observed in tumor tissue as compared to the control samples. Deficiency of ω-6 polyunsaturated fatty acids was noted in all tissue fragments. The specific features of fatty-acid composition of cervical cancer with different differentiation grade were found.

Keywords

• cervical cancer
• higher fatty acids