Indian Journal of Dermatology (Jan 2011)

Nephrogenic systemic fibrosis: A brief review

  • Rajesh Waikhom,
  • Abhijit Taraphder

DOI
https://doi.org/10.4103/0019-5154.77554
Journal volume & issue
Vol. 56, no. 1
pp. 54 – 58

Abstract

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Nephrogenic systemic fibrosis is a fibrosing disorder of the skin that develops in patients with advanced renal failure. It mostly presents with progressive hardening or induration of the skin of the extremities. Systemic involvement is also known to occur in this entity. Exposure to gadolinium contrast for radiological evaluation has been identified as the offending agent. The condition is progressive and can be seriously disabling. Therapeutic options are limited and not rewarding in majority of the cases. Awareness of this entity is important so that proper precautionary measures can be taken at the earliest to ameliorate the condition.

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