Multiple-cohort study of the elderly to determine the immunological characteristics and pathogenic mechanisms of severe community-acquired pneumonia caused by the low-virulence virus SARS-CoV-2 Omicron variant

• Tianyu Lu,
• Qiuhong Man,
• Shuai Xia,
• Xiaohang Liu,
• Yan Yan,
• Xueying Yu,
• Yan Fu,
• Wanli Liu,
• Lu Lu,
• Shibo Jiang,
• Lize Xiong

Affiliations

Tianyu Lu

Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences and Huashan Hospital, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, Fudan University

Qiuhong Man

Department of Laboratory Medicine, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University

Shuai Xia

Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences and Huashan Hospital, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, Fudan University

Xiaohang Liu

State Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua-Peking Center for Life Sciences, Institute for Immunology, Beijing Advanced Innovation Center for Structural Biology, Beijing Key Lab for Immunological Research on Chronic Diseases

Yan Yan

Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences and Huashan Hospital, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, Fudan University

Xueying Yu

Department of Laboratory Medicine, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University

Yan Fu

Department of Laboratory Medicine, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University

Wanli Liu

State Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua-Peking Center for Life Sciences, Institute for Immunology, Beijing Advanced Innovation Center for Structural Biology, Beijing Key Lab for Immunological Research on Chronic Diseases

Lu Lu

Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences and Huashan Hospital, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, Fudan University

Shibo Jiang

Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences and Huashan Hospital, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, Fudan University

Lize Xiong

Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center for Anesthesiology and Perioperative Medicine, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University