Nature Communications (Feb 2018)

Opponent control of behavioral reinforcement by inhibitory and excitatory projections from the ventral pallidum

  • Lauren Faget,
  • Vivien Zell,
  • Elizabeth Souter,
  • Adam McPherson,
  • Reed Ressler,
  • Navarre Gutierrez-Reed,
  • Ji Hoon Yoo,
  • Davide Dulcis,
  • Thomas S. Hnasko

DOI
https://doi.org/10.1038/s41467-018-03125-y
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 14

Abstract

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The ventral palladium (VP) is involved in reward and contains mostly GABAergic neurons, but also glutamatergic neurons. Here, the authors characterize glutamatergic VP neurons and show that glutamatergic versus GABAergic projections play roles in avoidance and reinforcement, respectively.