Nature Communications (Jan 2018)

One-step fermentative production of aromatic polyesters from glucose by metabolically engineered Escherichia coli strains

  • Jung Eun Yang,
  • Si Jae Park,
  • Won Jun Kim,
  • Hyeong Jun Kim,
  • Bumjoon J. Kim,
  • Hyuk Lee,
  • Jihoon Shin,
  • Sang Yup Lee

DOI
https://doi.org/10.1038/s41467-017-02498-w
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

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Fermentative production of aromatic polyesters from glucose has been unsuccessful. Here, the authors achieve the objective by one-step fermentation of metabolically engineered E. coli expressing a isocaprenoyl-CoA:2-hydroxyisocaproate CoA-transferase and an evolved polyhydroxyalkanoate synthase.