Viruses (Mar 2011)

A Strong Case for Viral Genetic Factors in HIV Virulence

  • Joshua T. Herbeck,
  • Viktor Müller,
  • Christophe Fraser

DOI
https://doi.org/10.3390/v3030204
Journal volume & issue
Vol. 3, no. 3
pp. 204 – 216

Abstract

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HIV infections show great variation in the rate of progression to disease, and the role of viral genetic factors in this variation had remained poorly characterized until recently. Now a series of four studies [1–4] published within a year has filled this important gap and has demonstrated a robust effect of the viral genotype on HIV virulence.

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