Linchuang shenzangbing zazhi (Jan 2015)
Clinicopathological analyses of aged nephrotic syndrome
Abstract
Objective To understand the nephritic syndrome in the elderly.Methods Clinicopathological analyses were performed on 287 patients with nephritic syndrome.According to the pathological WHO 1995 glomerular disease classification standard classification.Results In the 287 cases of nephrotic syndrome,61 cases were diagnosed in the elderly.Among them,53 cases(86.9%) had chronic glomerulonephritis,and 8 cases(13.1%) had secondary nephropathy.The clinical features presented little difference from those of younger patients,although 52.8%of the patients who had chronic glomerulonephritis manifested anemia,42.6%displayed acute renal insufficiency,and 6.6%displayed chronic renal insufficiency.59%of the patients manifested infection,and 11.5%displayed thrombus or embolism.Membranous nephropathy was the particularly common type in biopsy.Conclusions The nephrotic syndrome in elderly patients was not common and the clinical features differ little from those of younger patients,although complicated anemia,and renal insufficiency were more common than those in the young.The ratio of infection was higher than that in their younger counterparts.Chronic glomerulonephritis was the most common cause of the nephritic syndrome in the elderly.Membranous nephropathy was particularly common in the pathological detection.
