Nature Communications (Oct 2021)

Neuronal ribosomes exhibit dynamic and context-dependent exchange of ribosomal proteins

  • Claudia M. Fusco,
  • Kristina Desch,
  • Aline R. Dörrbaum,
  • Mantian Wang,
  • Anja Staab,
  • Ivy C. W. Chan,
  • Eleanor Vail,
  • Veronica Villeri,
  • Julian D. Langer,
  • Erin M. Schuman

DOI
https://doi.org/10.1038/s41467-021-26365-x
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 14

Abstract

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Ribosomes, assembled in the nucleus and perinuclear region, are thought to remain invariant throughout their lifetime. Here the authors document the dynamic association or exchange of ribosomal proteins within mature ribosomes of neuronal cells.