Iraqi Journal of Pharmaceutical Sciences (Mar 2017)

A Study of the Furocoumarin Derivative of Ruta Chalepensis L. (Rutaceae)

  • Ekbal H.AL-Khateeb,
  • Ali A. AL-Shamma,
  • Bajes A. Nehar

DOI
https://doi.org/10.31351/vol15iss1pp10-15
Journal volume & issue
Vol. 15, no. 1

Abstract

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The content of Furocoumarin derivatives (Psoralens) of Ruta Chalepensis L. (Whole plant) was studied by simple extraction with petroleum ether (b.p. 60-80Co). The results indicated that the plant contains a total of about (0.015%). Investigation of these compounds by thin layer chromatography (TLC) revealed the presence of at least four compounds of which methoxsalen (8-methoxypsoralen) was isolated. It was identified and authenticated with a standard by spectral method, IR, NMR, Mass spectra and HPLC.This plant could be considered as a good source for supplying this compound, which is widely used in dermatological preparations.