Nature Communications (Jun 2022)
Deep neural network trained on gigapixel images improves lymph node metastasis detection in clinical settings
- Shih-Chiang Huang,
- Chi-Chung Chen,
- Jui Lan,
- Tsan-Yu Hsieh,
- Huei-Chieh Chuang,
- Meng-Yao Chien,
- Tao-Sheng Ou,
- Kuang-Hua Chen,
- Ren-Chin Wu,
- Yu-Jen Liu,
- Chi-Tung Cheng,
- Yu-Jen Huang,
- Liang-Wei Tao,
- An-Fong Hwu,
- I-Chieh Lin,
- Shih-Hao Hung,
- Chao-Yuan Yeh,
- Tse-Ching Chen
Affiliations
- Shih-Chiang Huang
- Department of Anatomic Pathology, Linkou Chang Gung Memorial Hospital, Chang Gung University, College of Medicine
- Chi-Chung Chen
- aetherAI Co., Ltd.
- Jui Lan
- Department of Anatomic Pathology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine
- Tsan-Yu Hsieh
- Department of Anatomic Pathology, Keelung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine
- Huei-Chieh Chuang
- Department of Anatomic Pathology, Chiayi Chang Gung Memorial Hospital, Chang Gung University, College of Medicine
- Meng-Yao Chien
- aetherAI Co., Ltd.
- Tao-Sheng Ou
- aetherAI Co., Ltd.
- Kuang-Hua Chen
- Department of Anatomic Pathology, Linkou Chang Gung Memorial Hospital, Chang Gung University, College of Medicine
- Ren-Chin Wu
- Department of Anatomic Pathology, Linkou Chang Gung Memorial Hospital, Chang Gung University, College of Medicine
- Yu-Jen Liu
- Department of Anatomic Pathology, Linkou Chang Gung Memorial Hospital, Chang Gung University, College of Medicine
- Chi-Tung Cheng
- Department of Surgery, Linkou Chang Gung Memorial Hospital, Chang Gung University, College of Medicine
- Yu-Jen Huang
- Department of Computer Science and Information Engineering, National Taiwan University
- Liang-Wei Tao
- Department of Computer Science and Information Engineering, National Taiwan University
- An-Fong Hwu
- Department of Computer Science and Information Engineering, National Taiwan University
- I-Chieh Lin
- Department of Anatomic Pathology, Linkou Chang Gung Memorial Hospital, Chang Gung University, College of Medicine
- Shih-Hao Hung
- Department of Computer Science and Information Engineering, National Taiwan University
- Chao-Yuan Yeh
- aetherAI Co., Ltd.
- Tse-Ching Chen
- Department of Anatomic Pathology, Linkou Chang Gung Memorial Hospital, Chang Gung University, College of Medicine
- DOI
- https://doi.org/10.1038/s41467-022-30746-1
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 14
Abstract
The pathological identification of lymph node metastasis in whole-slide images is demanding and tedious. Here, the authors design an artificial-intelligence-assisted assessment workflow to facilitate the routine counting of metastatic LNs.