ACS Central Science (Oct 2021)
Engineered Ribosyl-1-Kinase Enables Concise Synthesis of Molnupiravir, an Antiviral for COVID-19
- John A. McIntosh,
- Tamas Benkovics,
- Steven M. Silverman,
- Mark A. Huffman,
- Jongrock Kong,
- Peter E. Maligres,
- Tetsuji Itoh,
- Hao Yang,
- Deeptak Verma,
- Weilan Pan,
- Hsing-I Ho,
- Jonathan Vroom,
- Anders M. Knight,
- Jessica A. Hurtak,
- Artis Klapars,
- Anna Fryszkowska,
- William J. Morris,
- Neil A. Strotman,
- Grant S. Murphy,
- Kevin M. Maloney,
- Patrick S. Fier
Affiliations
- John A. McIntosh
- Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, United States
- Tamas Benkovics
- Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, United States
- Steven M. Silverman
- Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, United States
- Mark A. Huffman
- Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, United States
- Jongrock Kong
- Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, United States
- Peter E. Maligres
- Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, United States
- Tetsuji Itoh
- Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, United States
- Hao Yang
- Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, United States
- Deeptak Verma
- Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, United States
- Weilan Pan
- Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, United States
- Hsing-I Ho
- Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, United States
- Jonathan Vroom
- Codexis, Inc., Redwood City, California, United States
- Anders M. Knight
- Codexis, Inc., Redwood City, California, United States
- Jessica A. Hurtak
- Codexis, Inc., Redwood City, California, United States
- Artis Klapars
- Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, United States
- Anna Fryszkowska
- Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, United States
- William J. Morris
- Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, United States
- Neil A. Strotman
- Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, United States
- Grant S. Murphy
- Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, United States
- Kevin M. Maloney
- Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, United States
- Patrick S. Fier
- Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, United States
- DOI
- https://doi.org/10.1021/acscentsci.1c00608
- Journal volume & issue
-
Vol. 7,
no. 12
pp. 1980 – 1985
Abstract
No abstracts available.
