Biological strategies in rotator cuff repair: a clinical application and molecular background

Abstract

Conventional repair of rotator cuff tears bears a variable but significant risk of incomplete healing. Biological therapies that accompany surgical rotator cuff repair include platelet-rich plasma, stem cells of different origins, and biological scaffolds. Biological therapies facilitate the regeneration of the correct microarchitecture of the tendon attachment to the bone and reduce failures after surgical rotator cuff repair.

Keywords

• rotator cuff repair
• biological therapy
• platelet-rich plasma
• stem cells
• bone marrow-derived stem cells
• adipocyte-derived stem cells
• biological scaffolds