Терапевтический архив (Oct 2010)

Efficiency of using cycloferon as part of combined therapy for chronic hepatitis C (a review of multicenter clinical trials)

  • Tamara Vasil'evna Sologub,
  • Mikhail Grigor'evich Romantsov,
  • Andrey Anatol'evich Shul'dyakov,
  • Yuliya Nikolaevna Lin'kova,
  • Valeriy Grigor'evich Radchenko,
  • Aleksey Leonidovich Kovalenko,
  • T V Sologub,
  • M G Romantsov,
  • A A Shuldyakov,
  • Yu N Linkova,
  • V G Radchenko,
  • A L Kovalenko

Journal volume & issue
Vol. 82, no. 10
pp. 78 – 78

Abstract

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The results of a study of the efficiency of treatment in patients with chronic hepatitis C conducted in a complex of multicenter clinical trials of the impact of various antiviral therapy regimens including the interferon genesis inductor cycloferon are reviewed. Four hundred and seventy-eight patients with hepatitis C virus infection were followed up. The study has demonstrated that the incorporation of cycloferon into the standard treatment regimen, which is manifested by the effect of drug synergism, by producing antiviral, immunomodulating, and antifibrotic effects, is a promising pharmacotherapy for chronic hepatitis C. This treatment is economically sound, reduces the incidence and degree of adverse reactions and increases the quality of life in the patients.

Keywords