Motriz: Revista de Educacao Fisica (Jun 2016)

Association of inflammation, dyslipidemia, obesity and physical activity status in children

  • Juliano Magalhães Guedes,
  • José Bontempo Mamêde Neto,
  • Alynne Christian Ribeiro Andaki,
  • Patrícia Feliciano Pereira,
  • Michelle Dias de Oliveira,
  • Roberto Sousa Dias,
  • Sérgio Oliveira de Paula,
  • Antônio José Natali,
  • Alexandre de Paula Rogério,
  • Edmar Lacerda Mendes

DOI
https://doi.org/10.1590/S1980-6574201600020003
Journal volume & issue
Vol. 22, no. 2
pp. 18 – 26

Abstract

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Abstract The aim of this study was to verify the association between inflammatory biomarkers, dyslipidemia, obesity and physical activity status in 10-years old children. Ninety-four children participated in this study and were classified into eutrophic (n=36), overweight (n=34) or obese (n=24) according to their body mass index (BMI). The genic expression of interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-α) and chemokine C-C motif ligand 2 (CCL-2) mRNA; the serum concentration of high-density lipoprotein cholesterol (HDL-c) and triglycerides; BMI, percentage of body fat (% BF) and waist circumference; and the number of steps per day were determined. The expression of IL-6, TNF-α and CCL-2 were associated (p 0.05) between pro-inflammatory biomarkers and number of steps per day was found.

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