Nature Communications (Nov 2020)

Developing a pathway-independent and full-autonomous global resource allocation strategy to dynamically switching phenotypic states

  • Junjun Wu,
  • Meijiao Bao,
  • Xuguo Duan,
  • Peng Zhou,
  • Caiwen Chen,
  • Jiahua Gao,
  • Shiyao Cheng,
  • Qianqian Zhuang,
  • Zhijun Zhao

DOI
https://doi.org/10.1038/s41467-020-19432-2
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 14

Abstract

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A challenge for biological chemical production is the completion between synthetic circuits and host resources. Here the authors the authors use quorum sensing circuits and global mRNA decay to independently control two phenotypic states.