Nature Communications (Aug 2016)
Sleep recalibrates homeostatic and associative synaptic plasticity in the human cortex
- Marion Kuhn,
- Elias Wolf,
- Jonathan G. Maier,
- Florian Mainberger,
- Bernd Feige,
- Hanna Schmid,
- Jan Bürklin,
- Sarah Maywald,
- Volker Mall,
- Nikolai H. Jung,
- Janine Reis,
- Kai Spiegelhalder,
- Stefan Klöppel,
- Annette Sterr,
- Anne Eckert,
- Dieter Riemann,
- Claus Normann,
- Christoph Nissen
Affiliations
- Marion Kuhn
- Department of Psychiatry and Psychotherapy, University Medical Center Freiburg
- Elias Wolf
- Department of Psychiatry and Psychotherapy, University Medical Center Freiburg
- Jonathan G. Maier
- Department of Psychiatry and Psychotherapy, University Medical Center Freiburg
- Florian Mainberger
- Department of Psychiatry and Psychotherapy, University Medical Center Freiburg
- Bernd Feige
- Department of Psychiatry and Psychotherapy, University Medical Center Freiburg
- Hanna Schmid
- Department of Psychiatry and Psychotherapy, University Medical Center Freiburg
- Jan Bürklin
- Department of Psychiatry and Psychotherapy, University Medical Center Freiburg
- Sarah Maywald
- Department of Psychiatry and Psychotherapy, University Medical Center Freiburg
- Volker Mall
- Department of Pediatrics, Technische Universität München
- Nikolai H. Jung
- Department of Pediatrics, Technische Universität München
- Janine Reis
- Department of Neurology, University Medical Center Freiburg
- Kai Spiegelhalder
- Department of Psychiatry and Psychotherapy, University Medical Center Freiburg
- Stefan Klöppel
- Department of Psychiatry and Psychotherapy, University Medical Center Freiburg
- Annette Sterr
- Department of Psychology, University of Surrey
- Anne Eckert
- Neurobiology Lab for Brain Aging and Mental Health, Transfaculty Research Platform University of Basel, Psychiatric University Clinics Basel
- Dieter Riemann
- Department of Psychiatry and Psychotherapy, University Medical Center Freiburg
- Claus Normann
- Department of Psychiatry and Psychotherapy, University Medical Center Freiburg
- Christoph Nissen
- Department of Psychiatry and Psychotherapy, University Medical Center Freiburg
- DOI
- https://doi.org/10.1038/ncomms12455
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 9
Abstract
Sleep deprivation is believed to lead to homeostatic increases in synaptic strength and reduced inducibility of associative LTP, based mainly on findings from animal studies. Here, Kuhn et al. demonstrate similar sleep-dependent synaptic plasticity changes in humans along with altered plasma BDNF levels.
