In vitro degradation behavior of oriented microcellular poly(L-lactic acid) biomimetic materials
Zhengqiu Li,
Yueling Chen,
Wenchao Yang,
Jingbiao Ye,
Xiangqian Song,
Ying Jin,
Xiaoqing Liu
Affiliations
Zhengqiu Li
Polymer and Composite Materials Division, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Zhejiang Provincial Key Laboratory of Bio-based Polymer Materials Technology and Application, Ningbo 315201, Zhejiang, China
Yueling Chen
School of Material Science and Engineering of Xihua University, Chengdu 610039, Sichuan, China
Wenchao Yang
School of Material Science and Engineering of Xihua University, Chengdu 610039, Sichuan, China
Jingbiao Ye
Hengdian Group TOSPO Engineering Plastics, Co., Ltd., Dongyang 322100, Zhejiang, China
Xiangqian Song
Hengdian Group TOSPO Engineering Plastics, Co., Ltd., Dongyang 322100, Zhejiang, China
Ying Jin
Hengdian Group TOSPO Engineering Plastics, Co., Ltd., Dongyang 322100, Zhejiang, China
Xiaoqing Liu
Polymer and Composite Materials Division, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Zhejiang Provincial Key Laboratory of Bio-based Polymer Materials Technology and Application, Ningbo 315201, Zhejiang, China
This paper investigated the static in vitro degradation behavior of poly(L-lactic acid) (PLLA)-oriented microcellular materials. The study compared the influence of different molecular chains and internal morphological structures on water penetration into the material. Also, the relationship between thse self-accelerated degradation caused by ester bond breakage and reduced material molecular weight and mechanical properties was explored. Furthermore, the mechanism behind the static in vitro degradation of oriented microcellular PLLA materials in simulated human body fluid was explored, laying the foundation for regulating the mechanical performance decline of oriented microcellular biomimetic bone repair materials to match specific bone healing periods.
