Alʹmanah Kliničeskoj Mediciny (Jul 2019)

The method of inhalation analgesia with sevoflurane during spontaneous delivery

  • E. Yu. Upriamova,
  • E. M. Shifman,
  • V. I. Krasnopol'skiy,
  • A. M. Ovezov,
  • S. V. Novikova,
  • I. I. Bocharova,
  • A. G. El'chaninova

DOI
https://doi.org/10.18786/2072-0505-2019-47-034
Journal volume & issue
Vol. 47, no. 3
pp. 196 – 203

Abstract

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Background: The search for methods for protection against delivery and labor pains has led to resumption of studies of non-invasive, safe and effective labor analgesia and inhalational anesthesia that could be used both separately and in combination with other methods. Recent research has demonstrated the highest efficacy of sevoflurane for analgesia of spontaneous delivery.Aim: To develop an optimized and effective method of inhalational analgesia with sevoflurane for spontaneous delivery.Materials and methods: We have performed a prospective study of the efficacy of inhalational sevoflurane for analgesia of spontaneous delivery. Thirty three obstetric patients were given sevoflurane-oxygen mixture according to a specially designed technique. The pain intensity was assessed with a visual analogous scale (VAS), sedation level, with Ramsay scale and Richmond Agitation-Sedation Scale (RASS).Results: The mean duration of inhalational anesthesia was 92.1±28 minutes [60–180']. There were no refusals and no switching to another type of analgesia. After induction of analgesia with Funding sevoflurane, there was a significant decrease of pain intensity by VAS by 34.9% from the baseline level (p = 0.00003); the pain was assessed as “moderate”. This trend was maintained throughout the whole exposure period.Conclusion: The results obtained confirm the possibility to use the proposed method of inhalational analgesia with sevoflurane to ensure effective analgesia in obstetric patients during delivery and labor.

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